W Taylor Kimberly Selected Research

Glyburide (Glibenclamide)

1/2022	Hypoxanthine is a pharmacodynamic marker of ischemic brain edema modified by glibenclamide.
3/2021	Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion.
2/2020	Poor Outcomes Related to Anterior Extension of Large Hemispheric Infarction: Topographic Analysis of GAMES-RP Trial MRI Scans.
1/2020	Role of Sulfonylurea Receptor 1 and Glibenclamide in Traumatic Brain Injury: A Review of the Evidence.
12/2019	BIIB093 (IV glibenclamide): an investigational compound for the prevention and treatment of severe cerebral edema.
11/2019	Intravenous Glibenclamide Reduces Lesional Water Uptake in Large Hemispheric Infarction.
1/2019	Anti-edema and antioxidant combination therapy for ischemic stroke via glyburide-loaded betulinic acid nanoparticles.
12/2018	Effect of IV glyburide on adjudicated edema endpoints in the GAMES-RP Trial.
1/2018	Long-Term Outcomes in Patients Aged ≤70 Years With Intravenous Glyburide From the Phase II GAMES-RP Study of Large Hemispheric Infarction: An Exploratory Analysis.
1/2018	Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date.

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W Taylor Kimberly Research Topics

Disease

34	Stroke (Strokes) 10/2022 - 09/2012
23	Edema (Dropsy) 01/2022 - 09/2012
19	Brain Edema (Cerebral Edema) 01/2022 - 08/2013
15	Ischemic Stroke 01/2022 - 01/2011
14	Infarction (Infarctions) 11/2021 - 01/2011
6	Brain Injuries (Brain Injury) 10/2022 - 01/2012
6	Alzheimer Disease (Alzheimer's Disease) 06/2005 - 03/2002
5	Brain Ischemia (Cerebral Ischemia) 01/2020 - 09/2012
5	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 01/2020 - 04/2015
3	Ischemia 03/2021 - 01/2014
3	Hydrocephalus (Hydrocephaly) 11/2019 - 04/2014
2	Neoplasms (Cancer) 01/2022 - 09/2021
2	COVID-19 09/2021 - 10/2020
2	Hemorrhage 01/2020 - 01/2017
2	Infections 04/2019 - 01/2016
2	Embolic Stroke 01/2019 - 05/2013
1	Hypertension (High Blood Pressure) 01/2022
1	Inflammation (Inflammations) 01/2022
1	Bronchiolitis Obliterans Syndrome 01/2022
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2021
1	Vascular System Injuries 12/2021
1	Cerebral Hemorrhage 01/2021
1	Hyperglycemia 01/2021
1	Critical Illness (Critically Ill) 09/2020
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2020
1	Brain Contusion 01/2020
1	Acute Liver Failure (Fulminant Hepatic Failure) 01/2020
1	Hepatic Encephalopathy 01/2020
1	Liver Diseases (Liver Disease) 01/2020
1	Coma (Comas) 01/2020
1	Liver Failure 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	Heart Arrest (Cardiac Arrest) 01/2018
1	Non-alcoholic Fatty Liver Disease 05/2017
1	Wounds and Injuries (Trauma) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 10/2016
1	Hypothermia 02/2016
1	Intracranial Vasospasm 06/2015

Drug/Important Bio-Agent (IBA)

18	Glyburide (Glibenclamide)FDA LinkGeneric 01/2022 - 09/2012
15	Biomarkers (Surrogate Marker)IBA 10/2022 - 01/2012
5	Sulfonylurea ReceptorsIBA 01/2020 - 09/2012
5	Matrix Metalloproteinase 9 (Gelatinase B)IBA 12/2018 - 09/2012
4	Pharmaceutical PreparationsIBA 10/2022 - 01/2014
4	Proteins (Proteins, Gene)FDA Link 04/2015 - 05/2003
3	Tissue Plasminogen Activator (Alteplase)FDA Link 06/2017 - 09/2012
3	Hemoglobins (Hemoglobin)IBA 06/2015 - 01/2011
3	Amyloid beta-PeptidesIBA 06/2005 - 05/2003
2	AntioxidantsIBA 10/2022 - 01/2019
2	Betulinic AcidIBA 10/2022 - 01/2019
2	Endothelin-1 (Endothelin 1)IBA 01/2022 - 09/2021
2	signal peptide receptorIBA 01/2022 - 09/2021
2	CytokinesIBA 12/2021 - 01/2021
2	Glucose (Dextrose)FDA LinkGeneric 11/2021 - 12/2014
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2020
2	Oxygen (Dioxygen)IBA 10/2020 - 01/2011
2	Biological ProductsIBA 12/2019 - 06/2005
2	Peptide Hydrolases (Proteases)FDA Link 11/2003 - 03/2002
2	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 05/2003 - 01/2003
1	Peptides (Polypeptides)IBA 10/2022
1	AcidsIBA 10/2022
1	Drug CarriersIBA 10/2022
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022
1	GuanosineIBA 01/2022
1	HypoxanthineIBA 01/2022
1	NucleosidesIBA 01/2022
1	PseudouridineIBA 01/2022
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 12/2021
1	LigandsIBA 09/2021
1	dimethylarginineIBA 01/2021
1	gluconic acid (gluconate)FDA LinkGeneric 01/2021
1	Fatty Acid-Binding ProteinsIBA 01/2021
1	Galectin 3 (LGALS3)IBA 01/2021
1	Uric Acid (Urate)IBA 01/2021
1	C-Reactive ProteinIBA 01/2020
1	Glutamine (L-Glutamine)FDA Link 01/2020
1	AmmoniaIBA 01/2020
1	Taurine FDA Link 11/2019
1	malic acid (malate)IBA 01/2019
1	Succinic Acid (Succinate)IBA 01/2019
1	Tricarboxylic AcidsIBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2018
1	anandamide (arachidonylethanolamide)IBA 05/2017
1	Warfarin (Coumadin)FDA LinkGeneric 01/2017
1	Membrane Transport Proteins (Biological Pump)IBA 12/2016
1	AldosteroneIBA 01/2016
1	IceIBA 01/2016
1	hemoglobin ASIBA 06/2015

Therapy/Procedure

10	Therapeutics 01/2022 - 04/2014
6	Decompressive Craniectomy 12/2016 - 04/2014
5	Thrombectomy 01/2022 - 06/2017
4	Critical Care (Surgical Intensive Care) 09/2020 - 04/2014
3	Ventriculostomy 04/2019 - 04/2014
2	Intravenous Administration 10/2022 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2019 - 01/2016
2	Embolectomy 10/2018 - 01/2018
2	Tracheostomy 08/2014 - 05/2014
1	Cell Transplantation 01/2022
1	Length of Stay 04/2019
1	Cardiopulmonary Resuscitation (CPR) 01/2018
1	Minimally Invasive Surgical Procedures 02/2016